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Wright and Aroda, 2020) reported that both oral and injectable semaglutide were mostly discontinued due to gastrointestinal adverse effects
That said, it remains in development, and further research is essential to fully establish its long-term safety and efficacy before it is brought to market
Contraindications Do not use DSIP if you: Are pregnant or breastfeeding (insufficient safety data) Have sleep apnea or other breathing-related sleep disorders (sedation risk) Take prescription sedatives or sleep medications Have a history of severe reactions to injected peptides Are under 18 years old If you have any chronic medical condition or take regular medications, consult a healthcare provider familiar with peptide therapies before starting DSIP
95% CI, 0.66-0.95) than those receiving DPP-4 inhibitors
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