The relevance of the trans-sulphuration pathway in the survival of cancer cells and reversion of ferroptosis was also proven by silencing CBS, thus inhibiting cysteine synthesis
This question nevertheless remains open and requires specific investigation
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Efinopegdutide is another GLP-1R and GCGR dual agonist currently under clinical investigation, which is being explored in studies for patients with obesity, type 2 diabetes (T2D), and metabolically associated fatty liver disease/multiple acyl-CoA dehydrogenase deficiency syndrome (MASLD/MASH)