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Science & References 1
Biogerontology
Because apparent clearance was 3441% lower in the youngest/lightest children, a weight-based (mg/kg) regimen was selected to achieve comparable systemic exposure across all ages and weights and for getting the target (about 4073% across bands) compared to placebo
Bosch G., et al
It was found that those with a high PRS had a greater risk of having PD than those with low PRS
doi: 10.1016/j.bbagen.2012.11.020 16
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