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Cold stress LAB used in food fermentation processes have their optimum growth temperature in mesophilic or thermophilic range and thus preservation methods essentially involving freezing, low temperature storage or freeze drying impart a certain degree of cold stress to the cells

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The standard dose then lands on 0.1 mL, or 10 units on a U-100 syringe

Furthermore, key secondary endpoints, including the percentage of patients achieving CRR with successful reduction of corticosteroid use and improvement in proteinuric response, were also met

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