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Representative drugs like the highly selective HIF-2 antagonist Belzutifan (MK-6482) [488] inhibit the expression of pro-angiogenic and pro-survival genes, alleviating abnormal metabolic burden and vascular disruption in tumor tissues
Czyrek AA, Baran K, Hruba E, Horackova A, Bosakova V, Chudzian J, Fafilek B, Laskova V, Stepankova V, Bednar D, Karl K, Kasparek P, Bosakova M, Killinger M, Szotkowska T, Prochazka J, Zieba JT, Rico-Llanos G, Fric J, Hadzic S, Loku E, Wujak M, Svozilova K, Stroblova M, Sedlacek R, Hristova K, Krakow D, Kubovciak J, Delattre M, Bartoszewski R, Buchtova M, Krowarsch D, Chaloupkova R, Zakrzewska M, Krejci P (2025) Increased thermal stability of FGF10 leads to ectopic signaling during development
"Delta Sleep Inducing Peptide (Emideltide)" Research Applications (Laboratory Use Only) Peptidereceptor interaction studies Neurotransmitter signaling pathway research Experimental investigations of circadian rhythm regulation Molecular studies of peptide-mediated cellular communication These applications are strictly confined to laboratory research and analytical investigations
comparison Two repair peptides with distinct literature emphases
doi: 10.1007/s00421-006-0354-y 52
doi:doi:10.1056/NEJMra2402527
