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Angiogenesis promotion is a theoretical concern for individuals with active or suspected cancer, and TB-500 should not be used by pregnant or breastfeeding individuals
Homotaurine, a safe blood-brain barrier permeable GABA(A)-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis
These combined actions have led to interest in its relevance for research models involving cardiovascular stress and impaired circulation.(23) Further animal-based investigations have reported protective effects in models of cardiac injury
Cell , 153(6), pp
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