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The in vivo evaluations demonstrated that Di-ART-GPC resulted in a reduced rate of ankle swelling and reduced inflammatory response compared to model controls and ART [90]

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Fluorescence emission of COX-2 FP was then tested in HCC cell lines and a heterograft mouse model, showing that both could be clearly distinguished from normal liver cells or tissues based on the fluorescence signal (Fig

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Rankings are based on five criteria: strength and reproducibility of the preclinical evidence base, existence of any human clinical data, specificity to musculoskeletal and connective tissue injury (rather than systemic or cosmetic endpoints), current regulatory and WADA status, and clarity of the dosing and stacking rationale available in the literature