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2021: Higher-dose semaglutide (Wegovy) for chronic weight management
It works by blocking opioid receptors, so if a person uses opioids while on naltrexone, they will not experience the euphoric effects
Research suggests that Zepbound (tirzepatide) produces more significant weight loss than Ozempic (semaglutide)
The goal of the study was to ascertain whether GI adverse events (GI AEs), such as nausea/vomiting, diarrhea, constipation, and dyspepsia (indigestion), during the dose escalation phase (baseline to week 12) and from baseline to the end of treatment, are responsible for the greater weight loss seen with semaglutide compared to other GLP-1RAs
Biological Psychology, 74 (1), 39-45
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