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These variants are pathway-level they don't predict response to any specific compound, but they describe the biology a clinician is prescribing into

(8) Mozaffarian, D., et al

Special Price 377.60 USD Product Information Product Name GLP-1 (7-37) peptide Documents Batch to batch variation of the purity Sequence Shortening H-HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG-OH Sequence H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH Length (aa) 31 Peptide Purity (HPLC) 95.73% Molecular Formula C 151 H 228 N 40 O 47 Molecular Weight 3355.65 Source Synthetic Form Powder Description GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion

These commonly include: Nausea often the most reported symptom, typically mild to moderate Vomiting less common but possible, particularly after eating too quickly or too much Diarrhoea or constipation bowel habit changes are frequently noted Bloating and indigestion a sensation of fullness or discomfort after meals Fatigue some patients report low energy levels in the early weeks These effects are generally transient and tend to improve as the body adapts to the medication

CT-388 (also known as RO7795068) is a signal-biased dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist developed by Roche/Genentech