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Another GLP agonist, lixisenatide (which is not approved for obesity), improved motor function in early Parkinsons disease (Meissner WG et al, N Eng J Med 2024;390:11761185)

A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors

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These symptoms are not always due to ischaemic optic neuropathy and often have other explanations, but they should never be ignored or left in the hope they settle. Mr Hove noted that any potential risk must be weighed against the well-established benefits of GLP-1 medications, which include improved blood sugar control, significant weight loss and a reduced risk of cardiovascular disease

Long-term use is associated with more serious effects, including osteoporosis, adrenal suppression, and increased susceptibility to infections

it is a fully synthetic medication manufactured using recombinant DNA technology in yeast cells