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Talenezhad N, et al
One trial evaluated TB4 for heart health, finding that the peptide could protect and repair the heart in patients with acute myocardial infarction, and a separate trial found that TB4 improved outcomes during congenital heart surgery.21 The review also mentions a few clinical trials related to eye health, with results showing that TB4 can reduce eye dryness, relieve ocular discomfort, lower inflammation in the conjunctiva, and more
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Notably, the stalk region and ECL1 are known to be important regulators for peptide hormone recognition and conformational dynamics 15,16
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