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When tumours reached ~100 mm 3 on average per genotype, animals were randomized by ranked allocation across all groups and given 5FU (10 mg kg 1 ), metformin (250 mg kg 1 ) or vehicle (PBS) daily by i.p
However, these described methods are not without insufficiencies that result from the complexities in IGF-1 as a peptide
The injections are usually given in your upper arm or thigh, or into a muscle
While treatments have come a long way, theres still room for improvement, especially regarding prevention
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References Bodamer OA, Hoffmann GF, Lindner M.: Expanded newborn screening in Europe 2007
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