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IFN-+NAC induced significantly more apoptosis compared to TNF-, IFN-, NAC, IL-6 + NAC, TNF-+NAC but lower than IL-6 (Fig
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The ototoxicity of aminoglycoside drugs is associated with a higher concentration of the drug in the internal lymph fluid, which impairs the energy production and utilization of the OHCs and causes dysfunction of Na + -K + -ATPase on the cell membrane, resulting in damage to HCs
