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Tirzepatide is a once-weekly, dual-incretin peptide it activates both the GIP and the GLP-1 receptor from a single molecule and in published obesity trials it has produced some of the largest average weight reductions of any incretin agent studied to date

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Reviews published in Kidney Research and Clinical Practice and the American Journal of Preventive Cardiology highlight the growing evidence supporting the use of GLP-1 receptor agonists in managing diabetic kidney disease and emphasize their potential to improve both kidney and heart health in patients with T2DM

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