Receptors for GIP, GLP-1 and glucagon are present in a wide variety of organs in addition to the pancreas, including fat tissue, bone and within the brain
They are optimized for different goals
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It is the source of fuel for mitochondria and is needed for the basic functioning of cells
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Graham DL, Durai HH, Trammell TS, Noble BL, Mortlock DP, Galli A, et al