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J Endocrinol 2006

(Clinical Pharmacologist) writes: Some Additional Insight into Bioavailability and Pharmacology Bioavailability is a measure of both the rate of absorption and the extent of absorption

Spontaneous reports through systems like the MHRA Yellow Card scheme cannot establish frequency or definitively confirm causality

Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila

Table 1 illustrates that the most significant obstacles to progress across these systems have not been a lack of physiological relevance, but unresolved pharmacologic, technological, or conceptual challenges