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DSIP short for delta sleep-inducing peptide is a compound patients increasingly ask about for sleep, usually after encountering it in longevity or biohacking content online

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In EVOKE and EVOKE+, oral semaglutide lowered several cerebrospinal-fluid markers of Alzheimers pathology, including phosphorylated tau and total tau, by up to roughly 10%, yet produced no measurable slowing of clinical decline

We remain optimistic that better and more relevant research can add more nuance to our understanding of the natural deterioration of human diastolic function, which in turn should improve the odds of finding effective treatments

While some patients may tolerate the combination, medical guidance helps prevent avoidable side effects and complications

doi:10.1038/s41392-024-01931-z Hui H, Farilla L, Merkel P, Perfetti R