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That work led to the discovery of glucagon-like peptide-1 (GLP-1), a hormone released from the small intestine that helps control insulin secretion, slow digestion and reduce appetite
10.1136/bmj-2022-072612 32 EbrahimiM.Akbari AsbaghF
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In the guidelines issued by the American Association of Clinical Endocrinologists (AACE), American Diabetes Association (ADA) and Chinese Diabetes Society, GLP-1RAs and SGLT-2is are the choice drugs in the case of metformin failure (Garber et al., 2019