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The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort, which may be more pronounced in post-bariatric patients

Everyone in these studies was given advice on lifestyle changes and was randomly assigned (by the flip of a coin) to take either Zepbound or a placebo, which is a substance with no real effect, for 72 to 88 weeks

Semaglutide GLP-1, Mounjaro, Wegovy, and Ozempic can all help patients achieve considerable weight loss, leading to dramatically improved health outcomes for overweight and obese patients

The original research focused on its role as a synthetic analog of the natural pineal peptide Epithalamin

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Blood 119 , 23682375 (2012)