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For continuation: evidence of at least 3 months on a stable dose and at least a 5% weight loss (for Wegovy/Zepbound), or 4% for Saxenda
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In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it
One-time prescribing has less value when tolerability and refill timing remain unresolved
doi: 10.1186/s12916-020-01688-6 157 KaiyalaKJPrigeonRLKahnSEWoodsSCSchwartzMW
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