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People using compounded versions should know they are taking a medication that hasnt been FDA approved and hasnt gone through the extensive testing typical for approved medications

Can I do low-carb (but not full keto) on GLP-1 medication

In line with strong and stable interactions of His1-Ala2 of GLP-1 compared with transient interactions of His1-Gly2 in exendin-4, truncation of these two N-terminal residues reduces GLP-1 affinity by 100300 fold, whereas for exendin-4, this has no effect, albeit, for both peptides, these residues are required for GLP-1R-mediated cAMP production 22,23,24,25

Park, S

doi: 10.1530/JOE-13-0221 87 HolstJ