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Effects on glucose metabolism Increased insulin secretion in a glucose-dependent manner Decreased glucagon secretion Increased insulin sensitivity Possible decrease in blood glucose due to the above-mentioned effects
For patients on mealtime insulin, the addition of a long-acting GLP-1 RA can result in a decreased need for prandial insulin
Bischoff SC: Gut health: a new objective in medicine
Math assumes the Phase 3 TRIUMPH titration above
Results of international, double-blind, randomized, placebo-controlled, phase IIa study of interleukin-1 blockade with RPH-104 (Goflikicept) in patients with ST-Segment-Elevation Myocardial Infarction (STEMI)
For individuals with obesity or overweight, a weekly 2.4 mg injection resulted in an average weight loss of approximately 15% of total body weight over 68 weeks
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