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References Standing Committee on the Scientific Evaluation of Dietary Reference Intakes - Panel on Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids and the Subcommittee on Upper Reference Levels of Nutrients, Food and Nutrition Board, Institute of Medicine (IOM)
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How MOTS-C Works Released from Mitochondria MOTS-C originates from the 12S rRNA of mitochondrial DNA, then enters cytosol and nucleus
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Standard Hill-equation pharmacology applied to retatrutides free-drug Cav,ss and the Coskun 2022 cAMP EC50 values (functional potency from low-receptor-density assays, used here as the occupancy denominator an approximation, not a binding constant)
doi: 10.1038/nrneph.2016.48 191 LanHY
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