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The largest trial involving DSIP to date, which included a total of 107 volunteers, reported that the peptide was generally well-tolerated with mostly minor side effects, which included [8]: Low blood pressure Increased sweating Headache Nausea Vertigo Considering that the drop in blood pressure was reported as moderate to severe in some patients, researchers should consider hypotension as a potentially exclusionary criterion for DSIP research
153 , 154 Kitagawa and coworkers 155 evaluated the conjugative properties of adamantine, a compound related to the drug memantine used for the treatment of Parkinsons disease
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These severe outcomes were associated with inappropriate use (e.g
