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Liraglutide in the treatment of heart failure: insight from FIGHT and LIVE
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These agents produced unprecedented weight-loss results, spurring an obsession with GLP-1 treatments among patients and physicians ( [3] )
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This causes ghrelin to rise and leptin to fall
We know how complex obesity and obesogenic environments are, and efforts to address obesity should not prioritize medications but rather consider the complex holistic and systemic changes in health environments, lifestyle factors, etc, to derive more sustainable benefits. Careful patient selection is also critical
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