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Common fillers that may cause reactions include: Lactose Cornstarch Polyethylene glycol (PEG) Povidone Carboxymethylcellulose Gelatin Dyes such as brilliant blue, sunset yellow FCF, allura red, indigo carmine Propylene glycol Mannitol Sucrose Compounding pharmacies, like CareFirst Specialty Pharmacy, can customize medications by removing fillers that may trigger mast cell activation
doi: 10.1073/pnas.1415518111 249 CaoYLiYHeCYanFLiJ-RXuH-Zet al
2% glutathione cream has been shown to be useful in some case of melasma
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doi: 10.3390/ijms22073603 92 Fratta PasiniA
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