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The study tested four different dosing regimens (100 mg, 300 mg, 600 mg daily, plus 400 mg daily in the extension Phase) against placebo, with primary outcomes measuring endoscopic response at 8 weeks and safety parameters at 60 weeks, while secondary outcomes included clinical remission, endoscopic remission, and mucosal healing
2018;155:458468.e8
Tirzepatide followed a similar pattern, though with some provincial formulary delays that affected actual patient access
3 Ascletis Pharma Inc
Actual dosing decisions depend on provider evaluation, patient tolerance, and treatment goals
