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These medications work by mimicking a natural gut hormone called glucagon-like peptide-1 (GLP-1), which helps control blood sugar levels 2 , slow down digestion, and reduce appetite 3
Due to oligo-ovulation or amenorrhea, PCOS leads to a decline in natural conception rates (79)
The Wegovy pill is an oral GLP1 medication taken once daily, while injectable Wegovy is administered weekly
The American Diabetes Association (ADA) guidelines recommend GLP-1 receptor agonists as preferred agents for patients with type 2 diabetes who have established atherosclerotic cardiovascular disease or indicators of high cardiovascular risk, or for those requiring additional glucose-lowering beyond metformin
However, the same neural regulation may manifest in some individuals as symptoms such as anhedonia, reduced motivation and low mood, which are precisely the important core manifestations of depressive disorders [34, 35]
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