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Potential endpoints include: Proteasome activity Ubiquitinated protein abundance Protein-degradation rates Misfolded-protein markers Autophagy-associated measurements Stress-response proteins Protein aggregation Cell viability under controlled stress Changes in proteostasis markers do not independently establish cellular rejuvenation or anti-aging effects
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In general, three phases of metabolic detoxification of xenobiotics have been often described in the literature
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The Renewal of Cells Skin health improves as a result of glutathione detoxification
Cell 166 , 935949 (2016)
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