Promising therapeutic strategies include natural inhibitors (e.g., baicalin, silymarin, quercetin), pharmacological inhibitors like chlormethiazole, and gene-targeting approaches such as clustered regularly interspaced short palindromic repeat (CRISPR)-associated nuclease 9 (Cas9)-mediated knockdown in preclinical models [107, 110112]
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2022) and play an integral role in multiple biological processes, including immune response, apoptosis, inflammatory response, and intercellular signal transduction (Kim et al
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