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Half of the samples were also incubated in 4 l of 10 mM TCEP (Sigma-Aldrich) at room temperature for 30 min, to reduce oxidized thiols

A study by Zhu et al (136) identified restoring RIPK3 expression to reverse R-2-hydroxyglutarate-induced necroptosis in isocitrate dehydrogenase-mutant AML cells as a potential therapeutic strategy for patients with AML

Choline magnesium trisalicylate at doses of 3,000 mg/day has resulted in impaired liver function, generalized itching, and ringing of the ears (tinnitus)

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