However, it has limited CNS bioavailability and lacks specificity, contributing to short-lived efficacy and side effects including confusion and hallucinations 60,61
Its popularity took off through word of mouth and social media rather than through large clinical trials, and that context matters
Furthermore, the epidermis is a formative barrier that functions in preventing diffusion of molecules to the underlying dermis [2, 3]
"Exosome therapy for androgenetic alopecia: Mechanisms of hair follicle regeneration." Journal of Cosmetic Dermatology , 23(4), 1256-1271
Tirzepatide activates both GIP and GLP-1 pathways, while semaglutide is a GLP-1 receptor agonist
But if you have high cholesterol, you're much better off getting most of these yellow nutrients from fruits and vegetables