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Huang et al., 2011
The other mechanism by which succinate supports tumorigenesis acts through the inhibition of hypoxia-inducible factor prolyl hydroxylase (PHD)
This dual-release strategy induces both apoptosis and ferroptosis, leading to synergistic killing of lung cancer cells, enhanced chemotherapeutic efficacy, and reduced toxicity to normal tissues
It is important to note that Hydroxocobalamin 20 mg/ml Injection Solution should not be used in patients with known hypersensitivity to hydroxocobalamin or any of the other ingredients in the solution
PloS One 11, e0167725
Role of Mitochondria in Ferroptosis
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