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Disadvantages include no additional support for common GLP-1 side effects
However, the phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year
Some people may need to continue taking semaglutide indefinitely
Some individuals report clothing fitting differently or slight visual changes in mirror assessment
So, while weight regain does happen, some patients do maintain meaningful weight loss over the long term
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