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The Gut-Brain Axis and the Vagus Nerve The GLP-1 produced in the intestines after a meal also plays a role in suppressing eating, likely through different circuits than those GLP-1-expressing neurons found in the brain stem

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Additionally, the protective effects of estrogens in PD are also related to the activation of the mitogen-activated protein kinase (MAPK) signaling pathway and the consequent upregulation of Bcl-2, as demonstrated in dopaminergic cells in mesencephalic slice cultures (Wang et al., 2011)

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