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The researchers noted that as patients lost weight, their thyroid levels changed and they often required levothyroxine dose modifications

Long-term deficiency can cause tingling, numbness, and in severe cases, irreversible nerve damage

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In fact, a 2026 large retrospective observational cohort study found no increased acute pancreatitis risk in type 2 diabetes patients using GLP-1RAs

Similar to GH abuse, acromegaly, a long-term condition in which the body tissues get larger over time, as well as non-reversible side effects to the heart, joints, and liver may occur

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