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Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study
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The phenomenon of ligand-directed signalling bias for GLP-1R has recently been described using the endpoints of cAMP production, pERK1/2 and intracellular Ca 2+
In the first phase of the current study, SR18, docked to GLP-1R, was subjected to 1 s MD simulations to directly compare its agonist-like properties with the established agonists and antagonists of GLP-1R reported earlier
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