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Tirzepatide (Mounjaro), a dual GIP/GLP-1 receptor agonist, shows dose-dependent nausea rates, ranging from approximately 12-18% at lower doses to higher rates at doses used for weight management, as demonstrated in the SURPASS-2 trial comparing it with semaglutide

Still, talk to your doctor about this symptom to rule out any underlying causes

Getting an eating disorder assessment is the only way to know for sure if you or a loved one has binge eating disorder or another type of eating disorder

And, if you do not have coverage for GLP-1 medications, remember that there are many safe, effective and affordable oral medications available as well

Dosing increases gradually: Treatment begins with a low dose and steps up slowly so the body has time to adjust

Conclusions GLP-1RA demonstrated phenotype-specific benefits, improving structural remodeling in HFpEF but showing limited effects in HFrEF