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Alternatively, pharmacological targeting of other players in the LE/Lys compartment that are intimately linked to Rab7 activity, including the mammalian target of rapamycin and vacuolar-type ATPase, or capable of modifying Rab7 activity through phosphorylation, palmitoylation and ubiquitination, could offer therapeutic opportunities [80, 81]
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4.0 4.1 4.2 Kushner RF, Jastreboff AM, Ryan DH (2025)
Subsequently, downstream events are activated
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