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Intracellular ferrous iron (Fe 2+ ) levels are tightly regulated through multiple mechanisms including import via transferrin receptor 1 and CD44, export via SLC40A1, storage via ferritin, lysosomal ferritinophagy mediated by NCOA4, and relocalization of iron to the cytosol [5]

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It is the only building block that contains sulfur, and without this building block, glutathione cannot be made

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