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It has shown immense promise in clinical trials: Patients lost on average around 50 percent more weight than those on the first generation of GLP-1 drugs like Ozempic

A medicine only helps if the patient actually takes it. When looking at the next research steps for elecoglipron, Carroll said he would like to see a phase 3 clinical trial involving thousands of patients over a year or more, to see where the blood-sugar and weight effects actually land and hold

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This narrow view overlooks how long-term use reduces total nutrient intake, not just calories

GLP-1 receptor agonists such as semaglutide are commonly prescribed for diabetes and obesity

no other pairwise contrasts were significant