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Several situations warrant pausing at a dose level for additional weeks before escalating: Persistent nausea: If nausea lasts beyond 2 weeks at any dose level, stay at that dose for an additional 2 to 4 weeks

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Hunterbrook also looked for cases where drugs were marked as available before again being designated unavailable and remained on the shortage list for years

They are not interchangeable research substrates

doi: 10.1093/jn/134.3.489

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