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There are no controlled human safety data on the fixed quadruple mixture, and all data summarized here come from preclinical or early-clinical individual studies on the components

2010 Apr;1(2):123-128

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J Am Coll Cardiol 63:11231133 Barrett P, MacDonald A, Helliwell R, Davidson G, Morgan P (1994) Cloning and expression of a new member of the melanocyte-stimulating hormone receptor family

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