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The trial was conducted in accordance with the Declaration of Helsinki (1996 revision) and under the principals of good clinical practice, as laid out in the International Conference on Harmonization document Good Clinical Practice Consolidated Guideline

Furthermore, reduced levels of the critical anti-aging factor sirtuin (SIRT)1, potentially due to repression by CCAAT/enhancer-binding-protein/histone deacetylase 1 (C/EBP-HDAC1) complexes, may contribute to accelerated liver aging (91)

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BPC-157 could potentially be used perioperatively to accelerate healing of intestinal anastomoses, skin grafts and surgical wounds

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10.1016/j.jhep.2019.02.014 11 Appiah-OpongR.CommandeurJ