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Insulin signaling in the brain is pivotal for cell survival, neuroinflammation, synaptic plasticity, and neurotransmission [6]
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Short-Term Effects of Liraglutide on Kidney Function and Vasoactive Hormones in Type 2 Diabetes: A Randomized Clinical Trial
Vagus nerve and underlying impact on the gut microbiota-brain axis in behavior and neurodegenerative diseases
New cases are being added steadily as more and more patients are experiencing the disadvantages of using GLP-1 drugs to lose weight
The STEP 1 trial (N=1,961) published in the New England Journal of Medicine in 2021 (DOI: 10.1056/NEJMoa2032183) demonstrated 14.9% mean body weight reduction with semaglutide 2.4mg weekly versus 2.4% with placebo over 68 weeks
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