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Common side effects include nausea, vomiting, diarrhea, and potential risks of pancreatitis and gallbladder disease

Extensive studies on its pharmacological properties have shown its anti-inflammatory, antioxidant, antinociceptive, antimicrobial, antiparasitic, antimalarial, and wound-healing properties

Interestingly, the CrAT activity is reduced during obesity and aging, leading to impaired glycemic control 65

115133 It is noteworthy that these data primarily derive from clinical trials in T2DM or obesity, and given the heterogeneity of metabolic disorders, caution should be exercised

If GSH peroxidase activity is deficient, lipid peroxidation could increase in the tissues, leading to increased stimulation of PGH synthase, increased thromboxane production, and further increase lipid peroxides