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Boehringer Ingelheim / Zealand Pharma (ZLDPF): Survodutide (aka BI 456906) [44] [44] In a placebo-controlled study evaluating the GLP1R/GR dual agonist (Obesity Indication), patients received weekly subcutaneous injections of 4.8mg for a duration of 46 weeks

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Obesity (Silver Spring) 19, 298304, doi: 10.1038/oby.2010.181 (2011)

Real-world usage involves side effects (nausea, vomiting), cost barriers, insurance coverage gaps, and the simple reality that taking a weekly injection indefinitely is harder than it sounds