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Summary: Patients with sulphonamide allergy must avoid all sulphonamide antibiotics (such as co-trimoxazole, sulfadiazine, and sulfamethoxazole), whilst non-antibiotic sulphonamides require individualised risk assessment as immunological cross-reactivity is unlikely but some products remain contraindicated

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Methylation reactions are vital for the production and the recycling of many important proteins, hormones, and neurotransmitters required for everyday bodily functions

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