These reductions represented estimated treatment differences ranging from 3.0% to 7.8% weight loss versus placebo, all of which were statistically significant
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So it's not that leptin is driving the body fat leptin is actually produced by body fat
However, it lacks the clinical trial data and regulatory approval of GLP-1 agonists, and its effects may be more modest
For Blue Cross, losses are likely to continue into this year, despite the insurer eliminating jobs, deploying computer algorithms to target doctors it believes are overcharging, restricting coverage of GLP-1 drugs for weight loss, and pushing back against health care providers seeking higher reimbursement rates
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