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There is no established clinical timeline, because the controlled trials that would establish one have not been done

However, food will not wholly absorb what you drink, and once alcohol hits your bloodstream, it will take effect

Data from similar medications shows that most people regain 70 to 80 percent of lost weight within 12 to 18 months of discontinuation

Expert Opinion on Investigational Drugs , 32(11)

Some people do less and some people do more

Once retatrutide is approved in the UK, a switch would normally involve stopping Mounjaro, a washout of around four to six weeks, and starting retatrutide at the lowest dose with slow titration